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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 10, No. 4, 2011, pp. 499-506
Bioline Code: pr11061
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 10, No. 4, 2011, pp. 499-506

 en Assessment of Heavy Metal Content of Branded Pakistani Herbal Products
Saeed, Muhammad; Muhammad, Naveed; Khan, Haroon & Zakiullah

Abstract

Purpose: To investigate the heavy metals present in branded Pakistani herbal medicines used in the management of various human ailments.
Method: The herbal dosage forms assessed were tablets, capsules and syrups. The samples were prepared for analysis by wet digestion method using nitric acid and perchloric acid treatment and then analyzed using a flame atomic absorption spectrometer.
Results: Most of the products exceeded the permissible limits for lead (100 %), cadmium (68 %), chromium (96 %) and nickel (100 %). However, the contents of copper, manganese, zinc and iron were below toxic limits in several of the products. Some of the products, including Arq-e-badian, Bazori, Banafsha and Arq-Mako, exhibited toxic concentration of almost all the metals assessed.
Conclusion: There is need to design suitable quality control parameters for the validation of herbal products and/or implement already existing rules and regulations for the safety of end-users.

Keywords
Heavy metals, Branded herbal products, Validation, Toxicity

 
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