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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 11, No. 3, 2012, pp. 461-467
Bioline Code: pr12056
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 11, No. 3, 2012, pp. 461-467

 en GC-MS Analysis of Insecticidal Essential Oil of Aerial Parts of Paederia scandens check for this species in other resources (Lour) Merrill (Rubiaceae)
Yang, Kai; Liu, Qi Zhi; Liu, Zhi Long & Du, Shu Shan

Abstract

Purpose: To investigate the chemical composition and insecticidal activity of the essential oil of the aerial parts of Paederia scandens check for this species in other resources against the maize weevil, Sitophilus zeamais.
Methods: Steam distillation of the aerial parts of P. scandens was carried out using Clavenger apparatus in order to obtain the volatile oils. Gas chromatography/mass spectrometric (GC/MS) analyses (HP-5MS column) of the essential oil were performed and its composition determined. Insecticidal activity of the essential oil was measured following topical application and seal-spaced fumigation.
Results: The main components of the essential oil were β-pinene (24.77 %), α-pinene (8.22 %), 1, 8- cineol (8.01 %), δ-terpinene (5.32 %), (E)-β-ocimene (5.21 %), linalool (4.92 %) and 4-terpineol (3.63 %). The essential oil exhibited strong fumigant toxicity against adult S. zeamais with LC50 (lethal concentration at 50 %) value of 7.14 mg/L air. P. scandens essential oil also possessed contact toxicity against S. zeamais with LD50 (lethal dosage at 50 %) value of 47.78 μg/adult insect.
Conclusion: The study indicates that the essential oil of P. scandens has a potential for development into a natural fumigant for control of insects in stored grains.

Keywords
Paederia scandens; Sitophilus zeamais; Essential oil, Contact toxicity, Fumigant.

 
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