The genus
Nephthea
is a member of the family
Acyonaceae, subfamily
Nephtheidae, and is distributed throughout the world mainly in the Indo-Pacific region. The genus Nephthea has been studied for its phytochemical constituents and these studies have resulted in the discovery of over a hundred compounds comprising amides, sesquiterpenes, diterpenes and steroids. Corresponding biological activities such as anti-inflammatory and cytotoxic activities have also been observed for some of the isolated constituents. Among the isolated constituents, steroids are the most abundant followed by diterpenes and sesqui biological activities reported for twelve species of the genus
Nephthea, namely,
Nephthea albida
,
Nephthea armata
,
Nephthea bayeri
,
Nephthea brassica
,
Nephthea capnelliformis
,
Nephthea crassica
,
Nephthea elongata
,
Nephthea erecta
,
Nephthea hainansis
,
Nephthea pacifica
,
Nephthea chabrolii
and
Nephthea sinulata
. The purpose of the review is to draw greater attention to the potentials of soft corals as a source of new drugs and secondary metabolites.
