|
Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 11, No. 5, 2012, pp. 855-866
|
Bioline Code: pr12101
Full paper language: English
Document type: Review Article
Document available free of charge
|
|
Tropical Journal of Pharmaceutical Research, Vol. 11, No. 5, 2012, pp. 855-866
en |
Poly(ethylene oxide)–Poly(propylene oxide)-Based Copolymers for Transdermal Drug Delivery: An Overview
Yapar, Evren Algin & İnal, Özge
Abstract
Amphiphilic poly(ethylene oxide)–poly(propylene oxide) (PEO–PPO)-based copolymers are
thermoresponsive materials having aggregation properties in aqueous medium. As hydrosolubilizers of
poorly water-soluble drugs and improved stability of sensitive agents, these materials have been
investigated for improvement in solubility, stability, release and bioavailability of drugs. The goal of the
present review is to summarize the properties of PEO–PPO based copolymers and highlight the works
that have been carried out on these materials for transdermal drug delivery.
Keywords
PEO–PPO based copolymer, Poloxamer, Hydrogel, Transdermal, Drug delivery.
|
|
© Copyright 2012 - Tropical Journal of Pharmaceutical Research Alternative site location: http://www.tjpr.org
|
|