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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 12, No. 3, 2013, pp. 323-327
Bioline Code: pr13050
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 12, No. 3, 2013, pp. 323-327

 en Enhancement of Human Cheek Skin Texture by Acacia Nilotica check for this species in other resources Bark Extract Cream
Ali, Atif; Akhtar, Naveed & Khan, Haji Muhammad S


Purpose: To evaluate the effect of a topical application of a cream formulation containing extract of Acacia Nilotica check for this species in other resources bark extract on human cheek skin texture.
Methods: A cream containing 3 % concentrated extract of Acacia nilotica bark was developed by entrapping the extract in the internal aqueous phase of the cream having strong antioxidant activity. A similar cream but without the extract was also prepared. Each of the formulations was applied to the cheeks of 11 human volunteers for a period of three months. Both cream formulations were assessed, using Visioscan VC 98, for various parameters including texture parameters (energy, contrast and variance) as well as for skin roughness (Ser), skin scaliness (SEsc), skin smoothness (SEsm) and skin wrinkles (Sew).
Results: Unlike the cream base, the extract cream exhibited steady, significant improvement in skin parameters over the 3-month period of application. Images showed visible improvement of the overall skin appearance and reduction of fine lines by the extract cream. Furthermore, skin texture (variance and contrast) and SELS (SEr, SEsc, SEsm and SEw) parameters showed significant decline (p < 0.05) and the texture parameter of energy showed significant increase (p < 0.05).
Conclusion: Our findings indicate that the cream containing 3 % Acacia nilotica bark extract possesses anti-aging effect and improves skin surface appearance.

Acacia nilotica; Cream; Anti-aging; Skin texture; Visioscan VC 98

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