search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 13, No. 8, 2014, pp. 1287-1293
Bioline Code: pr14177
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 13, No. 8, 2014, pp. 1287-1293

 en Antimicrobial and Antioxidant Activities of the Essential Oils of Some Aromatic Medicinal Plants ( Pulicaria inuloides check for this species in other resources -Asteraceae and Ocimum forskolei check for this species in other resources -Lamiaceae)
Al-Hajj, Nabil Qaid M.; Wang, Hong Xing; Ma, Chaoyang; Lou, Zaixiang; Bashari, Mohanad & Thabit, Riyadh

Abstract

Purpose: To determine the antimicrobial and antioxidant activities of Pulicaria inuloides check for this species in other resources and Ocimum forskolei essential oils.
Methods: Steam distillation of the aerial parts of P. inuloides and O. forskolei was performed using a Clevenger apparatus. Essential oils were analyzed by gas chromatography–mass spectrometry. Total phenolic content and antioxidant activities were determined by 2,2-diphenyl-1,1-picrylhydrazyl (DPPH) and β-carotene bleaching assays. Disc diffusion and microtiter broth microdilution assays were employed to determine antimicrobial activity.
Results: The chemical compounds in P. inuloides essential oil include 2-cyclohexen-1-one, 2-methyl-5- (1-methyl) (55.1 %) and benzene, methyl- (20.6 %). The major components identified in O. forskolei essential oil included bicyclo [3.1.1] hept-2-ene,2, (22.4 %) and naphthalene 1,2,3,4,4a,5,6, (19.3 %). P. inuloides showed a higher total phenol content than O. forskolei (144 ± 5.32 vs. 54.6 ± 30 mg GAE/g extract), higher antioxidant activity (92.92 ± 0.10 % vs. 26.76 ± 0.11 % scavenging activity; IC50, 4.5 ± 0.05 vs. 73.03 ± 0.05) and β-carotene bleaching (90.77 ± 0.21 % vs. 41.03 ± 6.35 % inhibition). P. inuloides essential oil inhibited all tested microorganisms except Salmonella typhimurium check for this species in other resources and Shigella dysenteriae check for this species in other resources with a minimum inhibitory concentration (MIC) of 3.0 μg/mL against Escherichia coli check for this species in other resources . O. forskolei essential oil inhibited only Candida albicans check for this species in other resources .
Conclusion: P. inuloides essential oil possesses significant antioxidant and antimicrobial activities.

Keywords
Essential oil; Phenolic content; Antioxidant; Antimicrobial activity; Pulicaria inuloides; Ocimum forskolei; Salmonella typhimurium; Shigella dysenteriae

 
© Copyright 2014 - Tropical Journal of Pharmaceutical Research
Alternative site location: http://www.tjpr.org

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2022, Site last up-dated on 27-Jul-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil