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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 13, No. 12, 2014, pp. 2021-2025
Bioline Code: pr14279
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 13, No. 12, 2014, pp. 2021-2025

 en Effect of Carvacrol on Salmonella check for this species in other resources Saintpaul Biofilms on Stainless Steel Surface
Uchida, Nancy Sayuri; Grespan, Renata; Piovezan, Michelle; Ferreira, Erika C.; Júnior, Miguel Machinski; Cuman, Roberto Kenji Nakamura & Mikcha, Jane Martha G.

Abstract


Purpose: To evaluate the effect of carvacrol against Salmonella check for this species in other resources saintpaul biofilms on stainless steel surface.
Methods: The effect of carvacrol on planktonic cells of S. saintpaul was evaluated by determining the minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). The action of carvacrol on S. saintpaul biofilms on stainless steel surface was evaluated on established biofilm and on biofilm formation by counting the number of bacterial cells that adhered to the surface and by scanning electron microscopy.
Results: The antimicrobial activity of carvacrol against planktonic cells of S. saintpaul was observed. The highest inhibitory effect of carvacrol was observed during biofilm formation at 78 and 117 μg ml-1 when S. saintpaul biofilms were reduced by 3 log cycles (p < 0.05).
Conclusion: Carvacrol reduced the number of bacterial cells that adhered to stainless steel surface, making it a potential compound for Salmonella saintpaul control.

Keywords
Salmonella spp.; Biofilm; Carvacrol; Antimicrobial activity; Planktonic cells; Stainless steel

 
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