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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 14, No. 6, 2015, pp. 1111-1117
Bioline Code: pr15146
Full paper language: English
Document type: Review Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 14, No. 6, 2015, pp. 1111-1117

 en Potential Beneficial Effects of Tulbaghia violacea check for this species in other resources William Henry Harvey (Alliaceae) on Cardiovascular System - A Review
Raji, Ismaila; Obikeze, Kenechukwu & Mugabo, Pierre

Abstract

Tulbaghia violacea check for this species in other resources William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low and middle - income countries. Furthermore, people in low-income countries are still largely dependent on plants in their surroundings for both prophylaxis and treatment of diseases, partly due to limited access to and cost of pharmaceuticals, and folkloric evidence of the potency of medicinal plants and/or local belief systems. Therefore, the present review aims to proffer possible ways by which T. violacea may improve cardi ovascular outcomes. An extensive and systematic review of the literature was carried out, and relevant findings presented in this review. There is evidence that T. violacea may modulate the renin-angiotensin system, the autonomic nervous system, oxidative stress and haemostasis, with resultant protection of the cardiovascular system in both health and disease.

Keywords
Tulbaghia violacea; Spontaneously hypertensive rats; Hypertension; Blood pressure; Heart rate; Renin - angiotensin aldosterone system

 
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