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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 14, No. 8, 2015, pp. 1517-1523
Bioline Code: pr15199
Full paper language: English
Document type: Review Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 14, No. 8, 2015, pp. 1517-1523

 en Ethnobotanical, Phytochemical and Pharmacological Aspects of Daphne Mucronata check for this species in other resources (Thymeleaceae)
Zaidi, Asma; Bukhari, Syed Majid; Khan, Farhan A.; Noor, Tayyaba & Iqbal, Naseem


Daphne Mucronata check for this species in other resources is a shrub well known as a medicinal plant in different regions of Asia. Ethnobotanical, phytochemical and pharmacological studies have revealed strong anti-cancer potential of the plant. Literature reports the evaluation of the initial bioactivity profile and extraction of the plant followed by different chromatographic techniques to obtain fractions. As an outcome, isolation and identification of coumarins, flavonoids, triterpenoids, lignin cumarinolignans, glucosides, daphnecin, aquillochin, daphnine and umbelliferone from the plant have been reported. Of these compounds, a diterpene, named gnidilatimonoein, has shown promising anticancer potency in in vitro tests on various cancer cell lines. This review article is an effort to summarize literature published in recent years on the bioactivity of Daphne mucronata.

Thymelaeaceae; Daphne mucronata; Diterpene; Gnidilatimonoein; Anti-cancer; Bioactivity

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