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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 14, No. 9, 2015, pp. 1691-1694
Bioline Code: pr15221
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 14, No. 9, 2015, pp. 1691-1694

 en Application of 99mTc-DTPA Radiotracer in Persian Cat’s Renal Scintigraphy
Assadnassab, Gholamreza & Oskoei, Shahram Dabiri

Abstract

Purpose: To evaluate the suitability of 99mTc-DTPA as a radiotracer in Persian cat's renal scintigraphy.
Methods: Twelve adult healthy Persian cats were selected. For scintigraphy, the animals were anesthetized and 99mTC-DTPA was injected via the femoral vein as a bolus at a dose of 1.5 mCi. Immediately after intravenous injection of radiotracer, scintigraphic operation was conducted on the renal organ. Administration of the radioisotope and accumulation of radioisotope in the tissues was monitored by specific imaging theemanating.
Results: Distinct scintigraphic scans were obtained using 99mTC-DTPA. Visual comparison of the scans indicates that there was no significant difference in the accumulation of radiotracer. In dynamic scans, symmetric and concurrent distribution of 99mTc-DTPA in the kidney was observed.
Conclusion: The results show that the radiopharmaceutical 99mTc-DTPA is suitable for use in Persian cat's renal scintigraphy, and this makes it potentially useful in research and clinical practice.

Keywords
Kidney; Persian cat; Radiotracer; Scintigraphy; Technetium-99m diethylene triamine pentacaetic acid (99mTc-DTPA)

 
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