Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
Vol. 15, No. 4, 2016, pp. 869-876
Bioline Code: pr16117
Full paper language: English
Document type: Research Article
Document available free of charge
Tropical Journal of Pharmaceutical Research, Vol. 15, No. 4, 2016, pp. 869-876
© Copyright 2016 - Tropical Journal of Pharmaceutical Research
Erectile dysfunction: prevalence, risk factors and involvement of antihypertensive drugs intervention|
Salman, Muhammad; Shehzadi, Naureen; Khan, Muhammad T.; Islam, Muhammad; Khan, Amer H. & Hussain, Khalid
To explore the literature regarding prevalance, risk factors and the involvement of
antihypertensive drugs in erectile dysfunction (ED).
Original research articles, reviews, editorials and case reports published in English language
on the prevalence of sexual/erectile dysfunction in hypertensive men taking antihypertensive drugs and
risk factors were identified through a search of four bibliographic databases, namely, PubMed,
EMBASE, CINAHL and EBSCO Health.
Recent analyses suggest that hypertensive men of almost all age groups suffer from ED but it
is more prevalent in elderly male patients. The involvement of β-blockers was found to be controversial.
Nevertheless, some evidence had been found regarding the use of propranolol in high doses.
The present review indicates the need for research to unravel the role of β-blockers in the
manifestation of ED in hypertensive males, whom there are no contributory factors such as sedentary
lifestyle, aging, stress and anxiety, etc.
Hypertension; Antihypertensive drugs; β-Blockers; Erectile dysfunction; Propranolol; Life styleRisk factors
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