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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 15, No. 9, 2016, pp. 2023-2027
Bioline Code: pr16267
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 15, No. 9, 2016, pp. 2023-2027

 en Clinical effect of Resina Draconis capsules on primary dysmenorrhoea
Sun, Li & Wang, Jia


Purpose: To examine the effectiveness of Resina Draconis capsules in the treatment of primary dysmenorrhoea.
Methods: In total, 324 patients with primary dysmenorrhoea were randomly allocated to three groups based on treatment with capsules containing Resina Draconis, Leonurus japonicus check for this species in other resources Houtt., or a placebo for 3 months. The patients’ visual analogue scale (VAS) scores and dysmenorrhoea symptoms were evaluated.
Results: VAS scores of the Resina Draconis, L. japonicus, and placebo groups decreased from 7.31 ± 1.36, 7.12 ± 1.65, and 7.25 ± 1.47 to 3.35 ± 1.43, 5.27 ± 1.24, and 7.08 ± 2.10, respectively. The change was greatest for the Resina Draconis group (p < 0.01). The incidence of symptoms associated with dysmenorrhoea decreased in all three groups, but the change was greatest for Resina Draconis group (p < 0.01). Overall, Resina Draconis was more effective than L. japonicus (94.40 vs. 72.20 %) (p < 0.05).
Conclusion: Resina Draconis capsules are effective in relieving primary dysmenorrhoea and lowering the incidence of symptoms associated with dysmenorrhoea.

Primary dysmenorrhoea; Resina Draconis; Leonurus japonicus Houtt; Visual analogue scale

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