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Iranian Journal of Pharmacology and Therapeutics
Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
ISSN: 1735-2657
Vol. 1, No. 1, 2002, pp. 1-4
Bioline Code: pt02001
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pharmacology and Therapeutics, Vol. 1, No. 1, 2002, pp. 1-4

 en Toxicity of Peganum harmala check for this species in other resources : Review and a Case Report
MASSOUD MAHMOUDIAN, HOSSEIN JALILPOUR and PIROOZ SALEHIAN

Abstract

Peganum harmala check for this species in other resources L. is a plant, which grows in semi-arid rangeland. The plant is used traditionally as an emmenagogue and an abortifacient agent in the Middle East and North Africa. All parts of plant are thoughtto be toxic and sever intoxication occurs in domestic animals. Digestive and nervous syndromes have been observed in animals that consume sub-lethal amount of the plant. The toxicated animal appears in a narcotic state interrupted by occasional short period of excitement. Abortion is frequent in animals that digest this plant in a dry year. While this plant has traditionally been used in Middle East, it shows toxic effects in human. A case of human overdose with P. harmala seeds is reported in this paper. Symptomsexperienced by our patient found to be similar to what has been reported for domestic animals.

Keywords
abortion, human toxicity, animal toxicity, hallucination

 
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Alternative site location: http://ijpt.iums.ac.ir/

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