Diuretic Activity of Sufoof-e-Suzak Qawi an Unani Polyherbomineral Formulation

The Suffof-e-Suzak Qawi is an unani polyherbomineral formulation and is being used in the alternative system of medicine for its anti-gonorrheal and diuretic activity. It is an official monograph in national formulary of unani medicine (NFUM) and reported as anti-gonorrheal and diuretic. The aqueous suspension of the formulation was studied for its possible diuretic activity and its effect on urinary sodium and potassium excretion. The results were compared with animal groups treated with vehicle and standard drug furosemide. When tested in healthy adult rats the formulation at a dose of 500, 750 and 1000 mg/kg has shown increase in the urinary output and urinary sodium excretion but not any increase in the urinary potassium excretion at all dose levels. The present study showed that, the aqueous suspension of Suffof-e-Suzak Qawi has diuretic activity comparable with the standard drug furosemide in producing urinary output and urinary sodium excretion and has no effect on urinary potassium excretion.