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Revista Colombia Médica
Universidad del Valle - Facultad de Salud
ISSN: 0120-8322
EISSN: 1657-9534
Vol. 32, No. 2, 2001, pp. 86-88
Bioline Code: rc01015
Full paper language: Spanish
Document type: Research Article
Document available free of charge

Revista Colombia Médica, Vol. 32, No. 2, 2001, pp. 86-88

 es Migrañ as: fisiopatologí a y tratamiento
Vladimir Zaninovic

Resumen

Aproximadamente 6% de los hombres y 18% de las mujeres sufren de migrañ as. Las investigaciones sugieren que en las migrañ as existe un estado de hipersensibilidad del sistema nervioso, al parecer, gené ticamente determinado. Se presentan los factores desencadenantes y la liberació n de neuropé ptidos, prostaglandinas, histamina y serotonina que estimulan las terminaciones sensitivas del trigé mino y producen el dolor. Se revisan los objetivos del manejo, las medidas de prevenció n y los fá rmacos má s usados para el tratamiento sintomá tico de las migrañ as.

Palabras-clave
Migraña. Factores desencadenantes. Fisiopatología. Prevención. Tratamiento. Sumatriptan.

 
 en
Vladimir Zaninovic

Abstract

About 6% of men and 18% of women suffer mygraine. Recent investigations suggest that a nervous system hypersensibility, possibly genetically determined is the main cause of mygraine. The main trigger factors and the liberation of neuropeptides, prostaglandins, histamine and serotonine appear to stimulate the trigeminal nerve endings where the pain is produced. The rational objectives of treatment, the prevention measures and the most frequently used drugs are briefly mentioned.

Keywords
Migraine. Triggers. Physiopatology. Prevention. Treatment. Sumatriptan.

 
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Alternative site location: http://colombiamedica.univalle.edu.co

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