Porphyromonas gingivalis
is implicated in chronic and aggressive periodontitis. This bacterium has numerous
virulence factors and one is the fimbriae, which is quite important for bacterial colonization. Fimbriae are
appendices that anchor to the bacterial wall and are comprised of the protein fimbriline encoded by the fimA
gene. Thus far, six genotypes have been identified, fimA I to V and Ib. Genotypes II and IV are associated with
periodontal disease, while genotype I is related to gingival health. Genotype identification of
P. gingivalis fimA
in periodontitis would be important to confirm the pathogenic genotypes and to establish risk at population
level. This review is about the
P. gingivalis fimA genotype prevalence worldwide. A systematic search using Pubmed,
Hinary, and Science Direct within the following descriptors:
Porphyromonas gingivalis, bacterial adhesion,
periodontitis, fimbriae, fimA, genotipification was performed to April 2011.
