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Revista Colombia Médica
Universidad del Valle - Facultad de Salud
ISSN: 0120-8322
EISSN: 1657-9534
Vol. 44, No. 1, 2013, pp. 51-60
Bioline Code: rc13010
Full paper language: English
Document type: Literature Review
Document available free of charge

Revista Colombia Médica, Vol. 44, No. 1, 2013, pp. 51-60

 en Functional differences of Porphyromonas gingivalis check for this species in other resources fimbriae in determining periodontal disease pathogenesis: a literature review
Moreno, Sandra & Contreras, Adolfo

Abstract

Porphyromonas gingivalis check for this species in other resources is implicated in chronic and aggressive periodontitis. This bacterium has numerous virulence factors and one is the fimbriae, which is quite important for bacterial colonization. Fimbriae are appendices that anchor to the bacterial wall and are comprised of the protein fimbriline encoded by the fimA gene. Thus far, six genotypes have been identified, fimA I to V and Ib. Genotypes II and IV are associated with periodontal disease, while genotype I is related to gingival health. Genotype identification of P. gingivalis fimA in periodontitis would be important to confirm the pathogenic genotypes and to establish risk at population level. This review is about the P. gingivalis fimA genotype prevalence worldwide. A systematic search using Pubmed, Hinary, and Science Direct within the following descriptors: Porphyromonas gingivalis, bacterial adhesion, periodontitis, fimbriae, fimA, genotipification was performed to April 2011.

Keywords
Porphyromonas gingivalis, bacterial adhesion, periodontitis, fimbriae, fimA, genotipification

 
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