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Iranian Journal of Reproductive Medicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433
EISSN: 2008-2177
Vol. 4, No. 2, 2006, pp. 77-79
Bioline Code: rm06015
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Reproductive Medicine, Vol. 4, No. 2, 2006, pp. 77-79

 en Short communication- Comparison of Anticardiolipin antibody and Antiphospholipid antibody in women with recurrent abortions
Seyed Mahmood Ghoraishian, Seyed Mehdi Klantar, Seyed Mohammd Seyed Hasani, Mohammad Ghafourzadeh

Abstract

Recurrent abortion is a critical problem in which many factors play a crucial role such as anticordiolipin antibody and antiphospholipid antibody. This study was conducted to evaluate the frequency of anticardiolipin antibody and antiphospholipid antibody in pregnancy failures in women with the history of recurrent pregnancy loss. In 154 women with the history of two or more recurrent pregnancy losses, serum anticardiolipin and serum antiphospholipid were measured using ELISA method. The positive IgG anticardiolipin and IgG antiphospholipid were detected in 12. 34% (19 patients) and 6.5% (10 patients) of patients respectively. Although 16 out of 19 patients with positive IgG anticardiolipin were negative for IgG antiphospholipid and 7 out of 10 patients with positive IgG antiphosphplipid were negative IgG anticardiolipin, but there was a significant correlation between IgG anticardiolipin and IgG antiphaspholipid ( r = 0.222 p=0.000). Our data concluded that anticardiolipin antibody is found to be more important than anti phospholipid antibody in recurrent abortion.

Keywords
Anticardiolipin antibody, Antiphospholipid antibody, Recurrent abortion

 
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Alternative site location: http://www.ijrm.ir

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