Perinatal complications associated with preterm deliveries at 24 to 33 weeks and 6 days gestation (2011- 2012): A hospital-based retrospective study|
Shariati, Maryam Khoshnood; Karimi, Zohreh; Rezaienejad, Mahroo; Azita, Basiri; Torkestani, Farahnaze & Gargari, Soraya Saleh
Background: Morbidity and mortality of preterm babies are important issues in
perinatal medicine. In developed countries, preterm delivery is the cause of about
70% of mortality and 75% of morbidity in the neonatal period, respectively.
Objective: The aim of this study was to determine the risk factors for preterm labor
and the outcomes, in terms of perinatal mortality and morbidity at the time of
discharge home, among preterm infants at less than 34 weeks gestation.
Materials and Methods: A retrospective study was conducted and all infants with a
gestational age of 24 to 33 weeks and 6 days who were born from November 1st
2011 to March 31, 2012 were enrolled in this study.
Results: From 1185 preterm infants were born during this period, 475 (40.08%)
infants with less than 34 weeks gestational age were included in the study. Our study
showed the major obstetrical risk factors for preterm labor were as follows:
preeclampsia (21%), premature rupture of membranes (20.3%), abruption of
placenta (10%), and idiopathic cases (48.7%). The neonatal mortality rate in less
than 34 weeks was 9.05%. Significant perinatal morbidity causesd in less than 34
weeks were as follows: sepsis (46.94%), respiratory distress syndrome (41.47%),
patent ductus arteriosus (21.47%), retinopathy of prematurity (3.57%), necrotizing
entrocolitis (1.68%), intra-ventricular hemorrhage (9%), and broncho-pulmonary
Conclusion: Preterm birth is associated with adverse perinatal outcome. This
situation needs to be improved by directing appropriately increased resources for
improving prenatal health services and providing advanced neonatal care.
Premature rupture of fetal membranes; Pre-eclampsia; Infant death; Respiratory distress syndrome; Necrotizing entrocolitis