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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433 EISSN: 1680-6433
Vol. 14, No. 9, 2016, pp. 603-606
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Bioline Code: rm16078
Full paper language: English
Document type: Case Report
Document available free of charge
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International Journal of Reproductive BioMedicine, Vol. 14, No. 9, 2016, pp. 603-606
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Fertility sparing surgery in gestational trophoblastic neoplasia: A report of 4 cases
Hasanzadeh, Malihe; Roodsari, Ftemeh Vahid; Ahmadi, Shahnaz; Mehr, Masoumeh Gavedan & Azadeh, Tabari
Abstract
Background: Gestational trophoblastic neoplasia (GTN) is a curable disease that
involves the development of malignant tumor in the woman after a normal or molar
pregnancy. The position of surgery in GTN is not properly specified and is changing
due to new chemotherapy protocols. However, the role of surgery is highlighted in
chemotherapy-resistant GTN. Other indications of surgery in trophoblastic diseases
are drug toxicity and uterine perforation. Based on the fact that most women in
certain age tend to preserve fertility, this study reported 4 cases of successful
treatment after fertility sparing surgery.
Case: A hospital-based case-report study was carried out to investigate the role of
surgery in 4 patients with GTN. In this study, acute complications, such as intraabdominal
bleeding and liver dysfunction due to chemotherapy occurred in some
patients. Surgery was performed and all cases underwent localized tumor removal
while preserving the uterus. No hysterectomy surgery was performed.
Conclusion: Surgery is supposed in specific cases of GTN, who desire preserving
fertility.
Keywords
GTT; Fertility; Surgery; Chemotherapy
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© Copyright 2016 - Iranian Journal of Reproductive Medicine Alternative site location: http://www.ijrm.ir
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