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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433 EISSN: 1680-6433
Vol. 15, No. 7, 2017, pp. 391-402
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Bioline Code: rm17050
Full paper language: English
Document type: Review Article
Document available free of charge
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International Journal of Reproductive BioMedicine, Vol. 15, No. 7, 2017, pp. 391-402
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Effectiveness of infertility counseling on pregnancy rate in infertile patients undergoing assisted reproductive technologies: A systematic review and meta-analysis
Maleki-Saghooni, Nahid; Amirian, Malihe; Sadeghi, Ramin & Roudsari, Robab Latifnejad
Abstract
Background: Psychological interventions such as counseling for infertile patients
seem to increase pregnancy rate.
Objective: The aim of this systematic review and meta-analysis was to examine if
counseling improves pregnancy rate among infertile patients. Thus, randomized
controlled trials investigating the effect of counseling on pregnancy rate in infertile
patients undergoing ART were pooled in a meta-analysis.
Materials and Methods: The databases of PubMed, Scopus, Cochrane, Google
Scholar, and Persian databases including SID, Iran Medex, and Magiran were
searched from 1997 to July 2016 to identify relevant articles. Included studies were
trials on infertile patients (women or couples) receiving counseling independent of
actual medical treatment. The outcome measure was pregnancy rate. Out of 620
relevant published trials, a total of nine RCTs were ultimately reviewed
systematically and included in a meta-analysis to measure the efficacy of counseling
on pregnancy rate. Odds ratio and Risk difference were calculated for pregnancy
rate. All statistical analyses were done by Comprehensive Meta-analysis Version 2.
Results: Nine RCTs involving 1079 infertile women/couples were included in the
study. The findings from RCTs indicated significant effect of counseling on
pregnancy rate so that there was a positive impact of counseling on pregnancy rate
(OR= 3.852; 95% CI: 2.492-5.956; p=0.00) and (RD= 0.282; 95%; CI: 0.208-0.355;
p=0.00).
Conclusion: Counseling was found to improve patients’ chances of becoming
pregnant. So counseling represents an attractive treatment option, in particular, for
infertile patients who are not receiving medical treatments.
Keywords
Counseling assisted reproductive techniques; Infertility; Meta-analysis; Pregnancy rates.
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