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Rwanda Medical Journal
Rwanda Health Communication Center - Rwanda Biomedical Center (RHCC - RBC)
ISSN: 2079-097X
Vol. 74, No. 4, 2017, pp. 6-8
Bioline Code: rw17020
Full paper language: English
Document type: Case Report
Document available free of charge

Rwanda Medical Journal, Vol. 74, No. 4, 2017, pp. 6-8

 en Cardio-respiratory complications in patients receiving Chloramphenicol in Rwanda: A case series
Sibomana, J. P.; Musabeyezu, E. & Donald, S.

Abstract

In low-resource settings, antibiotic policy is complicated by the constraints of multiple drug resistance and by lack of affordability for patents [1]. Chloramphenicol remains widely used in these settings as an effective treatment for a range of serious infections [2], [3]. Important serious adverse effects of chloramphenicol include bone marrow suppression and ‘grey baby’ syndrome [4]. We report here three cases in which chloramphenicol treatment was associated with severe acute systemic cardio-respiratory complications within the space of 6 months of each other.

Keywords
Chloramphenicol; Anti-bacterial agents; Drug-Related Side Effects; Adverse Reactions; Developing Countries

 
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