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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 2, No. 2, 2005, pp. 122-128
Bioline Code: tc05014
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 2, No. 2, 2005, pp. 122-128

 en Research Paper- EVALUATION OF ANALGESIC, ANTICONVULSANT AND HYPNOTIC ACTIVITIES OF PYRENACANTHIA STAUNDTII
Awe, E. O; Makinde, J. M.b; Olajide, O. A; Wahkee, O .Ka; Adeloye, A. O.

Abstract

An Aqueous leaf extract of Pyrenacanthia Staundtii check for this species in other resources (AqPs) was studied for central nervous activities. The extract (100.0 -400.0 mg/kg i. p). significantly (p<0.05) inhibited acetic-acid induced abdominal constriction, and both the early and or late phases of formalin-induced paw licking in mice. AqPs (100-400mg/kg i.p.) also demonstrated a protective effect against strychnine-induced convulsion. The extract potentiated the hypnotic effect of hexobarbitone following i.p. injection at the dose levels studied. The results suggested that AqPs possesses potential analgesic, anticonvulsive and hypnotic properties.

Keywords
Pyrenacanthia staundtii, Analgesic activity, Anticonvulsive, Hypnotic effects.

 
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