A questionnaire-guided ethno-medical survey of the Igede speaking communities of Benue state (Nigeria) was conducted. 90 plant species from 45 families were identified covering 109 recipes against 35 ailments, including internal, external infections and parasitic diseases as well as poisons, pesticides, cuisine and for veterinary purposes. Ageratum conyzoides
was the only plant used in HIV/AIDS disease. Mode of preparation, dosage regimen, plant(s) and part(s) used are reported. The importance of this kind of documentation in research and bio-conservation are discussed.