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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 1, 2006, pp. 75-81
Bioline Code: tc06008
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 1, 2006, pp. 75-81

 en ANTIMALARIAL ACTIVITY OF SWARTZIA MADAGASCARIENSIS check for this species in other resources DESV. (LEGUMINOSAE), COMBRETUM GLUTINOSUM check for this species in other resources GUILL. & PERR. (COMBRETACEAE) AND TINOSPORA BAKIS check for this species in other resources MIERS. (MENISPERMACEAE), BURKINA FASO MEDICINAL PLANTS.
Y. Ouattara, S. Sanon, Y. Traoré, V. Mahiou, N. Azase, L. Sawadogo

Abstract

Swartzia madagascariensis check for this species in other resources , Combretum glutinosum check for this species in other resources and Tinospora bakis check for this species in other resources are three plants of the folk medicine used by healers in Burkina Faso for the treatment of malaria. A scientific validation of this utilization was not previously made. Aqueous, methanol, hydromethanol extracts from the roots bark of S. madagascariensis, methanol and hydromethanol extracts from the leaves of C. glutinosum and aqueous and alkaloidal extracts from the roots of T. bakis were also made and their antimalarial activity was screened against Plasmodium falciparum check for this species in other resources chloroquine-resistant strain W2 in vitro. The screening showed that the methanol and hydromethanol extracts of Swartzia madagascariensis, hydromethanol extracts of Combretum glutinosum and alkaloidal extracts of Tinospora bakis were active(5μg/ml < IC50 < 50 μg/ml).

Keywords
Antimalarial activity; Swartzia madagascariensis; Combretum glutinosum; Tinospora bakis.

 
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