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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 2, 2006, pp. 21-26
Bioline Code: tc06028
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 2, 2006, pp. 21-26

 en ANTIDIABETIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF Croton zambesicus check for this species in other resources MUELL.(THUNDER PLANT) IN ALLOXAN DIABETIC RATS
J. E. Okokon, A. L. Bassey and J. Obot

Abstract

Antidiabetic activity of ethanolic leaf extract of Croton zambesicus check for this species in other resources Muell. Arg. was evaluated using alloxan-induced (150mg/kg) hyperglycaemic rats. The activity of the ethanolic leaf extract was compared with that of a reference drug Chlorpropamide. The Blood Glucose Levels were measured using glucometer. The extract produced a significant (P<0.01) reduction in BGL after a single dose of the extract and in prolonged treatment (for 7 days). The antidiabetic activity was comparable to that of the reference drug-chlorpropamide.

Keywords
Croton zambesicus,antidiabetic, alloxan

 
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