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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 3, 2006, pp. 32-36
Bioline Code: tc06034
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 3, 2006, pp. 32-36

 en Short Communication- IN VITRO CYTOTOXIC ACTIVITY OF EXTRACTS OF MARCHANTIA CONVOLUTA check for this species in other resources ON HUMAN LIVER AND LUNG CANCER CELL LINES
Xiaoqing Chen and Jianbo Xiao

Abstract

The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to test cytotoxicity of the extracts from Marchantia convoluta check for this species in other resources against two human cancer cell lines (H1299 and HepG2). Low concentrations of theethyl acetate extract had toxic effects on HepG2 cells and inhibited H1299 cells at higher concentration. Inhibition of proliferation and induction of cell death were in a concentration-dependent. However, the petroleum ether and n-butanol extracts of Marchantia convoluta showed no cytotoxic activity.

Keywords
Cytotoxicity test; MTT assay; Marchantia convoluta

 
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