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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 3, 2006, pp. 59-69 		Bioline Code: tc06037
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 3, 2006, pp. 59-69

 en ANTIMICROBIAL AND BRINE SHRIMP LETHALITY OF EXTRACTS OF TERMINALIA MOLLIS check for this species in other resources LAWS
Mainen J. Moshi, Zakaria H. Mbwambo, Modest C. Kapingu, Viva H. Mhozya, Chacha Marwa

Abstract

Using the disc diffusion method it was demonstrated that extracts of the leaves, stem and roots of Terminalia mollis check for this species in other resources Laws (Combretaceae) have antibacterial activity against Staphylococcus aureus check for this species in other resources (NCTC 6571), Escherichia coli check for this species in other resources (NCTC 10418), Pseudomonas aeruginosa check for this species in other resources (NCTC 10662), Klebsiella pneumoniae check for this species in other resources (NCTC 9633), Salmonella typhi check for this species in other resources (NCTC 8385), and Bacillus anthracis check for this species in other resources (NCTC 10073) and antifungal activity against Candida albicans check for this species in other resources (Strain HG 392), and local strains of Aspergillus flavus check for this species in other resources and Cryptococcus neoformans check for this species in other resources . The root extracts were the most active followed by the stem, and leaf extracts.Extracts of the three parts also exhibited cytotoxicity to brine shrimp larvae with LC50 values ranging from 26.3 to 58.1, l0.4 to 69.5, and 42.9-101.3μg/ml, for the root, stem, and leaf extracts, respectively. The results support the traditional uses of extracts of this plant for the management of bacterial and fungal infections.

Keywords
Terminalia mollis, Antimicrobial activity, Traditional medicine.

 
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