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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 3, No. 4, 2006, pp. 43-49
Bioline Code: tc06051
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 3, No. 4, 2006, pp. 43-49

 en ANTIMALARIAL ACTIVITY OF MAMMEA AFRICANA check for this species in other resources
Jude E. Okokon; Aniekan E. Udokpoh; Grace A. Essiet

Abstract

The antimalarial activity of ethanolic stembark extract of Mammea africana check for this species in other resources was studied in vivo in mice infected with Plasmodium berghei berghei check for this species in other resources berghei during early and established infections.Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood schizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine,5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.

 
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