The antimalarial activity of ethanolic stembark extract of
Mammea africana
was studied in vivo in mice infected with
Plasmodium berghei berghei
berghei during early and established infections.
Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood schizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine,5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.
