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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 4, No. 1, 2007, pp. 17-22
Bioline Code: tc07015
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 4, No. 1, 2007, pp. 17-22

 en EVALUATION OF 17 MEDICINAL PLANTS FROM NORTHERN CÔTE D'IVOIRE FOR THEIR IN VITRO ACTIVITY AGAINST STREPTOCOCCUS PNEUMONIAE check for this species in other resources
W. Mamidou Koné, K. Kamanzi Atindehou, A. Kacou-N'Douba, and M. Dosso

Abstract

Twenty crude extracts from 17 species out of 11 families were assessed for their antibacterial activity against Streptococcus pneumoniae check for this species in other resources (Pneumococcus). The selected plants are used in Northern Côte d'Ivoire to treat various infections including respiratory track diseases. From all the tested extracts, only 7 from 6 plants showed a promising in vitro bactericidal activity against Peumococcus, including strains resistant to penicillin. The most active extracts were from Erythrina senegalensis check for this species in other resources (Fabaceae), Piliostigma thonningii check for this species in other resources (Caesalpiniaceae), Waltheria indica check for this species in other resources (Sterculiaceae), Andira inermis check for this species in other resources (Fabaceae), Uapaca togoensis check for this species in other resources (Euphorbiaceae), Keetia hispida check for this species in other resources (Rubiaceae) and Combretum molle check for this species in other resources (Combretaceae). This is the first time that the antipneumococcal activity of the tested plants is reported. The results of this preliminary investigation support the traditional use of these plants in the treatment of pneumococcal infections. The most active of them could be candidates for isolation of compounds which could serve as lead structures for the development of new drugs against Streptococcus pneumoniae.

Keywords
Antibacterial activity ; Côte d'Ivoire ; Medicinal plants ; Pneumococcus ; Streptococcus pneumoniae.

 
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