search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 4, No. 3, 2007, pp. 372-376
Bioline Code: tc07037
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 4, No. 3, 2007, pp. 372-376

 en ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITS
Ogbole, O. O.; Ekor, M. N.; Oluremi, B. B.; Ajaiyeoba, E. O.; Gbolade, A. A.; Ayoola, M. A. & Adeyemi, A. A.

Abstract

The methanolic extracts of HIPPOCRATEA INDICA check for this species in other resources root bark and Poga oleosa check for this species in other resources fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus check for this species in other resources being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans check for this species in other resources . These results confirm the anti-inflammatory and antibacterial activities of the two plants.

Keywords
Hippocratea indica, Poga oleosa, anti-inflammatory, antimicrobial

 
© Copyright 2007 - African Journal Traditional, Complementary and Alternative Medicines
Alternative site location: http://journals.sfu.ca/africanem/index.php/ajtcam

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil