The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of
Acacia nilotica
,
Justicia zelanica
,
Lantana camara
and
Saraca asoca
exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 μg/ml and 75.0-300.0 μg/ml against the bacterial and fungal pathogens, respectively. The other extracts of
Phyllanthus urinaria
,
Thevetia nerifolia
,
Jatropha gossypifolia Saraca asoca,
Tamarindus indica
,
Aegle marmelos
,
Acacia nilotica
,
Chlorophytum borivilianum
,
Mangifera indica
,
Woodfordia fruticosa
and
Phyllanthus emblica
showed antimicrobial activity in a range of 75-1200 μg/ml.