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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 4, No. 4, 2007, pp. 510 – 523
Bioline Code: tc07068
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 4, No. 4, 2007, pp. 510 – 523

 en IN VITRO ANTIMICROBIAL ASSAY OF PLANTS USED IN TRADITIONAL MEDICINE IN BUKOBA RURAL DISTRICT, TANZANIA.
Kisangau, D.P.; Hosea, K.M.; Joseph, C.C. & Lyaruu, H.V.M.

Abstract

Plants used in traditional medicine in Bukoba Rural district in Tanzania were evaluated for their in vitro antimicrobial activities. Plant materials from eight plant species ( Harungana madagascariensis check for this species in other resources (Lam) Poir., Jatropha curcas check for this species in other resources L., Lantana trifolia check for this species in other resources L., Plectranthus barbatus check for this species in other resources Andr., Pseudospondias microcarpa check for this species in other resources Engl., Psorospermum febrifugum check for this species in other resources Spach, Teclea nobilis check for this species in other resources Del. and Vernonia adoensis check for this species in other resources [Warp.] SL) were collected based on ethnomedical information provided by traditional herbal practitioners. Results of the study indicate that extracts from the eight plant species were active against at least one or more of the test organisms ( Bacillus subtilis, check for this species in other resources Staphylococcus aureus check for this species in other resources [gram positive], Escherichia coli check for this species in other resources , Pseudomonas aeruginosa check for this species in other resources [gram negative] and Candida albicans check for this species in other resources [Yeast]). A profile of secondary metabolites (alkaloids, terpenoids, triterpenes, phenolics, tannins, flavonoids, anthraquinones, flavonols/flavones and /or chalcones, sterols and saponins) was obtained for three plant species ( Jatropha curcas check for this species in other resources L., Plectranthus barbatus check for this species in other resources Andr., and Pseudospondias microcarpa check for this species in other resources Engl.). The paper discusses the probable therapeutic basis of these traditional plants based on their secondary metabolite profiles and for the first time draws research attention to Bukoba Rural district as a source for plants with potential pharmaceutical applications.

Keywords
Antimicrobial activity, Secondary metabolites, Traditional medicine, Tanzania.

 
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