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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 5, No. 2, 2008, pp. 209-212
Bioline Code: tc08029
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 5, No. 2, 2008, pp. 209-212

 en Anti-Nociceptive and Anti-Inflammatory Activities of Ethanol Extract of Syzygium check for this species in other resources Flower Bud in Wistar Rats and Mice
Tanko, Y.; Mohammed, A.; Okasha, M. A.; Umar, A. H & Magaji, R. A

Abstract

The ethanol extracts of Syzygium check for this species in other resources flower bud were tested for anti-nociceptive and anti-inflammatory effects in mice and Wistar rats which were carried out using acetic acid-induced abdominal contractions in mice and formalin-induced hind paw edema in Wistar rats. Three doses of the ethanol extract (50, 100, and 200mg/kg body weight i.p.) were used for both studies. The extract had an LD50 of 565.7 mg/kg body weight intraperitoneally in mice. The extracts produced significant effect (P<0.05) at all the three doses. Similarly, the anti-nociceptive activity produced significant effects (P<0.05) at all the three doses of the extract. The result supports the local use of the plant in painful and inflammatory conditions.

Keywords
Syzygium aromaticum flower bud,anti-inflammatory, anti-nociceptive; Anti-Inflammatory; Acetic acid-induced abdominal constriction.

 
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