The hypoglycaemic and antihyperglycaemic properties of the aqueous extracts of the leaves of
Ageratum Conyzoides
L. were evaluated in normoglycemic and in streptozotocin-induced diabetic rats, in order
to validate its use in folk medicine. Tested animals were given the aqueous extracts of the plant at the doses of
100, 200 and 300mg/kg. These doses were tested also on glucose loaded normal male rats (Oral Glucose
Tolerance Test). Of all the doses, the aqueous extracts at 200 and 300mg/kg showed statistically significant
hypoglycaemic and antihyperglycaemic activities. For the oral glucose tolerance test, 100mg/kg dose only
attenuated significantly the rise of blood glucose in normal fasted rats. Consequently, these results confirmed the
hypoglycaemic properties of the leaves of
Ageratum conyzoides.
