The effect of ethanolic leaf extract of
Lasianthera
Africana
on experimentally induced ulcer was studied in
rats. The extract (1000 3000mg/kg) inhibited ethanol-induced, indomethacin induced and reserpine induced
ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.01).
The effect of the extract was comparable to that of the standard drugs used. Thus,
Lasianthera africana extract
demonstrated a good antiulcer activity which supports the antiulcer effect of this plant in traditional medicine.