African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
Vol. 7, No. 4, 2010, pp. 286-290
Bioline Code: tc10041
Full paper language: English
Document type: Research Article
Document available free of charge
African Journal of Traditional, Complementary and Alternative Medicines, Vol. 7, No. 4, 2010, pp. 286-290
© Copyright 2010 Afr. J. Trad. CAM.
Use Of Strychnos nux-vomica (Azraqi) Seeds In Unani System Of Medicine: Role Of Detoxification|
Akbar, Seema; Khan, Shamshad A.; Masood, Akbar & Iqbal, M.
Some plants used in Unani system of medicine are toxic, even deadly poisonous. The drugs having such plants as their components are detoxified before they are dispensed to the patients. One such drug, capsule Hudar, has Strychnos nux-vomica L. (Azraqi) seeds as one of its components and is very effectively used to elevate blood pressure. Ancient manuscripts describe many methods of its detoxification. It has been found that the detoxification processes studied reduce the strychnine content, as determined either by using uv-vis spectrophotometer or HPLC, present in Strychnos nux vomica seeds which is responsible for Strychnos nux vomica toxicity. The decrease in strychnine amount was best when the seeds were immersed for detoxification in excess of water for 5 days, in milk for 2 days followed by their boiling in milk. Strychnine in small amounts has been reported to give subjective feeling of stimulation
Strychnos nux vomica; detoxification; Unani medicine
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