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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 8, No. 4, 2011, pp. 387-390
Bioline Code: tc11049
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 8, No. 4, 2011, pp. 387-390

 en Preliminary Phytochemical Screening and Antimicrobial Evaluation of Three Medicinal Plants used in Nigeria
Baba, Haruna & Onanuga, Adebola

Abstract

Methanol extract of three Nigerian medicinal plants were screened for antimicrobial activity using modified Kirby-Bauer disc diffusion and agar dilution techniques to determine the diameters of zone on inhibition and minimum inhibitory concentrations (MIC)of the extracts respectively. The extract of each of the plants were tested against five clinical bacterial isolates comprising of two Gram-positive bacteria ( Bacillus subtilis check for this species in other resources and Staphylococcus aureus check for this species in other resources ) and three Gram-negative bacteria ( Pseudomonas aeruginosa check for this species in other resources , Escherichia coli check for this species in other resources and Klebisella pneumonia check for this species in other resources ) organisms. All the extracts exhibited moderate to high level of antimicrobial activities against these microorganisms. Phytochemical screening of the powdered plant material revealed the presence of some secondary metabolites such as alkaloids, saponins, tannins, anthraquinones and flavonoids. These Nigerian medicinal plants could be developed into cheap, safe and culturally acceptable standardized herbal products and may served as source of new molecules for broad-spectrum antimicrobial agents.

Keywords
Dissotis rotundifolia; Costus lucanusianus; Solenostemon monostachys; Methanol extract; Antimicrobial activity

 
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