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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 9, No. 1, 2012, pp. 56-58
Bioline Code: tc12008
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 9, No. 1, 2012, pp. 56-58

 en FLAVONOIDS FROM SUDANESE ALBIZIA ZYGIA check for this species in other resources (LEGUMINOSAE, SUBFAMILY MIMOSOIDEAE), A PLANT WITH ANTIMALARIAL POTENCY
Abdalla, Muna Ali & Laatsch, Hartmut

Abstract

Three flavonoids were isolated for the first time from the Sudanese medicinal plants Albizia zygia check for this species in other resources . Compounds 1-3 were identified by interpretation of ESI mass data, 1H, 13C and 2D NMR as well as by comparison with published data as 4',7-dihydroxyflavanone (1) 3',4',7-trihydroxyflavone (2), 3-O-methylfisetin (3',4',7-trihydroxy-3-methoxyflavone, 3). All flavonoids were tested against Plasmodium falciparum check for this species in other resources , and only compound 2 showed high antimalarial activity (IC50 0.078 μg/ml).

Keywords
Albizia zygia; Mimosoideae; flavonoids; antimalarial activity

 
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