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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 3, 2013, pp. 427-430
Bioline Code: tc13054
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 3, 2013, pp. 427-430

 en ANTILEISHMANIAL ACTIVITY OF SOME PLANTS GROWING IN ALGERIA: JUGLANS REGIA check for this species in other resources , LAWSONIA INERMIS check for this species in other resources AND SALVIA OFFICINALIS check for this species in other resources .
Serakta, M.; Djerrou, Z.; Mansour-Djaalab, H.; Kahlouche-Riachi, F.; Hamimed, S.; Trifa, W.; Belkhiri, A.; Edikra, N. & Hamdi Pacha, Y.

Abstract

The current study was undertaken to evaluate in vitro the antileishmanial activity of three plants growing wild in Algeria : Juglans regia check for this species in other resources , Lawsonia inermis check for this species in other resources and Salvia officinalis check for this species in other resources . The hydroalcoholic extracts of these plants were tested on the growth of the promastigotes of Leishmania major. The plant extract effects were compared with three controls : CRL1 composed of 1 ml RPMI inoculated with 106 of promastigotes, CRL2 composed of 1 ml RPMI inoculated with 106 of promastigotes and 100 μl of hydroalcoholic solvent, CRL3 composed of 1 ml RPMI inoculated with 106 of promastigotes and 100 μl of Glucantim as a reference drug in the management of leishmaniasis. The results showed that both J. regia and L. inermis extracts reduced the promastigotes number significantly (P<0.01). however, S. officinalis showed a total inhibition of the Leishmania major growth.

Keywords
anti-leishmanial activity; Leishmania major; Juglans regia; Lawsonia inermis; Salvia officinalis

 
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