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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 3, 2013, pp. 458-468
Bioline Code: tc13059
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 3, 2013, pp. 458-468

 en EVALUATION OF ANTI-BACTERIAL AND WOUND HEALING ACTIVITY OF THE FRUITS OF AMORPHA FRUTICOSA check for this species in other resources L.
Qu, Xueling; Diao, Yunpeng; Zhang, Zhen; Wang, Shouyu & Jia, Yujie

Abstract

As the traditional Chinese medicine, the fresh fruits of Amorpha fruticosa check for this species in other resources L. were applied for the treatment of carbuncle, eczema and burn (Das et al., 2007). However, little is known about the functional roles of the fruits of Amorpha fruticosa L. during wound healing progress. In the present study, we evaluated both antimicrobial potential against a wide range of microorganisms and wound healing activity of the seven compounds isolated from the fruits of Amorpha fruticosa L in vitro and in vivo. Our results showed that compounds I (6a,12a–dehydroamorphin), V (dehydrosermundone) and VI (tephrosin) isolated from the fruits of Amorpha fruticosa L. performed dominant antimicrobial potential against microorganisms. Moreover, these compounds significantly enhanced fibroblasts proliferation and migration, leading to promotion of wound healing. Thus, it could be possible for the therapeutic utilization of Amorpha fruticosa L. for wound healing in the future.

Keywords
Amorpha fruticosa L; anti-bacterial; wound healing

 
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