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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 3, 2013, pp. 512-517
Bioline Code: tc13066
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 3, 2013, pp. 512-517

 en STUDY ON IN-VIVO ANTI-TUMOR ACTIVITY OF VERBENA OFFICINALIS check for this species in other resources EXTRACT
Kou, Wei-Zheng; Yang, Jun; Yang, Qing-Hui; Wang, Ying; Wang, Zhi-Fen; Xu, Su-Ling & Liu, Jing

Abstract

We investigated the anti-tumor effects of Verbena officinalis check for this species in other resources extract on H22 tumor-bearing mice and its effect on immune function. Mice model of H22 solid tumor was established, the mice were divided into five groups and administered the extract, later, tumors were removed and inhibition rates were calculated; spleens were removed and spleen indices were calculated, and the sheep red blood cell-delayed-type hypersensitivity (SRBC-DTH) and the serum hemolysin level were determined. The Verbena officinalis extract had anti-tumor effect, with the inhibition rate reaching 38.78%, it also increased the spleen index to a certain extent, in addition, the changes in DTA and HA were not obvious compared with the model group. The Verbena officinalis extract had in vivo anti-tumor effect, while causing no damage on the immune function.

Keywords
Verbena officinalis extract; H22 mouse; tumor inhibition; immune function

 
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