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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 5, 2013, pp. 230-235
Bioline Code: tc13109
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 5, 2013, pp. 230-235

 en EFFECTS OF METHANOLIC EXTRACT OF MORINGA OLEIFERA check for this species in other resources LEAVES ON SEMEN AND BIOCHEMICAL PARAMETERS IN CRYPTORCHID RATS
Afolabi, Ayobami Oladele; Aderoju, Hameed Adeola & Alagbonsi, Isiaka Abdullateef

Abstract

While anti-oxidant effects of Moringa oleifera check for this species in other resources in much oxidative stress related diseases have been well reported, cryptorchidism on the other hand has been shown to cause oxidative stress. However, study is scanty on the likely role of Moringa oleifera in reducing cryptorchidism-induced oxidative stress in rats has not been studied. The present study looked into the effects of methanolic extract of Moringa oleifera leaves (MEMO) on semen and biochemical parameters in cryptorchid rats. Twenty male albino rats (200-250g) were randomly divided into 4 groups (n=5 each). Groups A and B were sham-operated and treated with corn-oil and 200mg/kg of MEMO respectively, while groups C and D were rendered cryptorchid and also treated with corn-oil and 200mg/kg of MEMO respectively. Cryptorchid rats had lower testicular weight, sperm count, germ cell count, testicular superoxide dismutase (SOD) concentration, testicular total protein and higher testicular malondialdehyde (MDA) concentration compared to sham-operated rats. MEMO had no significant effect on testicular weight and MDA concentration, while it significantly increased sperm count, germ cell count, testicular SOD and total protein in the cryptorchid rats. The present study suggests that MEMO ameliorates cryptorchidism associated germ cell loss and oxidative stress.

Keywords
Antioxidants; Cryptorchidism; Moringa oleifera; Oxidative stress; Sperm count; Germ cell count

 
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