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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 5, 2013, pp. 256-260
Bioline Code: tc13112
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 5, 2013, pp. 256-260

 en A STUDY ON ANTICANCER ACTIVITY OF CAULIS SPATHOLOBI check for this species in other resources EXTRACT ON HUMAN OSTEOSARCOMA SAOS-2 CELLS
Liu, Bo; Liu, Jinlan; Chen, Jing; Zhu, Dongmei; Zhou, Huajiang & Wang, Ximing

Abstract

The objective of the present study was to investigate the anticancer activity of Chinese medicine Caulis Spatholobi check for this species in other resources extract on multicentric osteosarcoma cells. Ultraviolet spectrophotometry was used to determine the total flavonoid content in each sample; vanillin sulphuric acid assay was used to determine the condensed tannin content in each sample; and the varying degrees of inhibitory activities of ethanol, ethyl acetate and n-butanol extracts of Caulis Spatholobi on human osteosarcoma Saos-2 cells were studied. The results showed that the inhibitory activity of ethyl acetate extract was the highest among the four extracts. The condensed tannin contents of 1.2 mg/mL Caulis Spatholobiwater extract, ethanol extract, ethyl acetate extract and petroleum ether extract were 26.23%, 48.36%, 70.18% and 40.51% respectively; and condensed tannin content of 1.5 mg/mL Caulis Spatholobi water extract, ethanol extract, ethyl acetate extract and petroleum ether extract were 4.15%, 5.81%, 8.76% and 7.30% respectively.

Keywords
Caulis Spatholobi; Inhibitory activities; Osteosarcoma cells

 
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