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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 5, 2013, pp. 341-344
Bioline Code: tc13126
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 5, 2013, pp. 341-344

 en ANTI-BACTERIAL ACTIVITIES AND PHYTOCHEMICAL SCREENING OF EXTRACTS OF DIFFERENT PARTS OF THALICTRUM RHYNCHOCARPUM check for this species in other resources
Mayeku, Philip Wafula; Hassanali, Ahmed; Kiremire, BernardTuryagenda; Odalo, Josiah Ochieng & Hertweck, Christian

Abstract

Parts of the plant Thalictrum rhyncocarpum check for this species in other resources are used in herbal medicine in Kenya to treat various infections. The aim of this study was to evaluate in-vitro anti-bacteria activities and phytochemical profiles of solvent extracts of the leaves, stem bark and root of Thalictrum rhyncocarpum against Bacillus subtilis check for this species in other resources -6633, Staphylococcus aures check for this species in other resources -SG 511, Escherichia coli check for this species in other resources SG 458, Pseudomonus aeruginosa check for this species in other resources -K799/61 and Mycobacterium vaccae check for this species in other resources -10670. Anti-bacterial activity tests were carried out using disc diffusion assay and tube dilution technique, and phytochemical screening was carried out through Thin Layer Chromatography. The crude extracts showed antibacterial effects on M. vaccae, P. aeruginosa and B. subtilis. M. vaccae was most sensitive, particularly to the methanol root extract. Phytochemical screening of the extracts suggested the presence of glycosides and alkaloids in the stem bark and root extracts, and flavonoids and triterpenes in the leaf extracts. The study showed interesting levels of activities of solvent extracts of different parts of T. rhyncocarpum against some of the bacteria tested (M. vaccae, P. aeruginosa and B. subtilis). The results provide some scientific rationale for the traditional use of the plant in Kenya to treat different microbial infections.

Keywords
Thalictrum rhyncocarpum; Ethno-medicinal plant,; Anti-microbial activities; Phytochemical profile

 
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