The objective of the study was to investigate the anti-tumour effect of ethanol extract of
Solanum lyratum
Thunb. in S
180 tumour-bearing mice, and to preliminarily explore its mechanism of action. Methods: Mice were made into S
180 solid tumour model, grouped and administered. Tumour inhibition rate was measured by harvesting the tumours. Serum IL-2, TNF-a contents were measured by taking blood samples, and thymus index and spleen index were measured by harvesting the thymus and spleen. The results showed that the
Solanum lyratum Thunb. extract had certain tumour inhibitory effect, which can elevate the serum IL-2, TNF-a contents, and increase the thymus and spleen indices to a certain extent. The study concluded that
Solanum lyratum Thunb. extract has certain
in vivo anti-tumour effect which may be exerted through enhancing the body immunity.
