The objective of the study was to investigate the anti-tumour effect of ethanol extract of Solanum lyratum
Thunb. in S180
tumour-bearing mice, and to preliminarily explore its mechanism of action. Methods: Mice were made into S180
solid tumour model, grouped and administered. Tumour inhibition rate was measured by harvesting the tumours. Serum IL-2, TNF-a contents were measured by taking blood samples, and thymus index and spleen index were measured by harvesting the thymus and spleen. The results showed that the Solanum lyratum
Thunb. extract had certain tumour inhibitory effect, which can elevate the serum IL-2, TNF-a contents, and increase the thymus and spleen indices to a certain extent. The study concluded that Solanum lyratum
Thunb. extract has certain in vivo
anti-tumour effect which may be exerted through enhancing the body immunity.