The objective of this paper was to study the therapeutic effect of Stigma maydis
polysaccharides in diabetic mice. Mouse models of types 1 and 2 diabetes were established. The body weight, food intake, water intake as well as blood sugar level and glucose tolerance of mice were measured. Stigma maydis
polysaccharides can improve the symptoms of weight loss and polydipsia in diabetic mice, and had an obvious antagonistic effect on alloxan-induced hyperglycaemia. The glucose tolerance test also showed that the Stigma maydis
polysaccharides had very good effects on suppression and prevention of acute hyperglycaemia. Stigma maydis
polysaccharides have some improvement effect on alloxan-induced types 1 and 2 diabetes.