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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 6, 2013, pp. 435-438
Bioline Code: tc13143
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 6, 2013, pp. 435-438

 en A STUDY ON THE INHIBITORY EFFECT OF MATRINE ON GASTRIC CANCER SGC-7901 CELLS
Song, Shimao; Zhu, Shengming; Zhang, Zhiguo; Mo, Zhengying; Ke, Qing & Luo, Zhiguo

Abstract

The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.

Keywords
Matrine; SGC-7901; MTT assay

 
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Alternative site location: http://journals.sfu.ca/africanem/index.php/ajtcam

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