Aiming at the exploration of herbal use by society, crude extracts of the seeds of some commonly used medicinal plants (
Vitis vinifera
,
Tamarindus indica
and
Glycin max
) were screened for their free radical scavenging properties using ascorbic acid as standard antioxidant. Free radical scavenging activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The overall antioxidant activity of grape seeds (
Vitis vinifera) was the strongest, followed in descending order by soybean (
Glycin max) and tamarind (
Tamarindus indica). The seeds extract of
Vitis vinifera,
Glycin max and
Tamarindus indica showed 85.61%, 83.45% and 79.26%, DPPH scavenging activity respectively.