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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 10, No. 6, 2013, pp. 532-537
Bioline Code: tc13162
Full paper language: English
Document type: Review Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 10, No. 6, 2013, pp. 532-537

 en A REVIEW OF THE PHARMACOLOGICAL MECHANISM OF TRADITIONAL CHINESE MEDICINE IN THE INTERVENTION OF CORONARY HEART DISEASE AND STROKE
Zhang, Wenting; Gao, Kuo; Liu, Jingwei; Zhao, Huihui; Wang, Juan; Li, Yubo; Murtaza, Ghulam; Chen, Jianxin & Wang, Wei

Abstract

In recent years, several researches have showed that Buyang Huanwu Decoction (BHD) possesses multiple target points in the intervention of diseases, and has same treatment effects on cerebrovascular diseases and cardiovascular diseases. But, there was no full report about the mechanistic and material basis in Brain-Heart concurrent treatment. The objective of the present study was to examine the pharmacological mechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. We combined the HIT, PubChem, David Database resource and the networked pharmacology method to ultimately find out BHD’s thirty-five potential brain-heart concurrent treatment target points, and preliminarily reveal BHD’s material basis for treatment of cerebrovascular diseases and cardiovascular diseases. Finally, the study provided new information with the guidance meanings.

Keywords
Buyang Huanwu Decoction (BHD); Brain-Heart concurrent treatment; Pharmaceutical effect mechanism; Material basis

 
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Alternative site location: http://journals.sfu.ca/africanem/index.php/ajtcam

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