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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 11, No. 1, 2014, pp. 23-27
Bioline Code: tc14003
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 11, No. 1, 2014, pp. 23-27

 en THE ANTIBACTERIAL ACTIVITY OF TRADITIONALLY USED SALVADORA PERSICA check for this species in other resources L. (MISWAK) AND COMMIPHORA GILEADENSIS check for this species in other resources (PALSAM) IN SAUDI ARABIA
I. I. Al-sieni, Abdulbasit

Abstract

Background: Nowadays there is a need to find naturally occurring substances from plants with antimicrobial activity as an alternative to available used antibiotics.
Materials and Methods: Salvadora persica check for this species in other resources (miswak) and Commiphora gileadensis check for this species in other resources were collected, dried and extracted with either methanol or warm water and the obtained extracts were assessed for their antibacterial activity against 5 different genera of bacteria using agar well diffusion method. The tested bacteria included some human pathogens.
Results: The obtained extracts exhibited considerable inhibitory effects against all the tested bacteria with various degrees of growth inhibition. It was shown that methanol extract was more effective compared to water extracts. The minimum inhibitory concentrations (MIC) of the methanol extracts ranged from 50-100 μg/ml. No toxicity was found using Artemia salina check for this species in other resources as test organism and no antitumor activity against Ehrlich ascites carcinoma.
Conclusion: S. persica and C. gileadensis showed moderate to high inhibitory activity on pathogenic bacteria with no toxicity and can be used traditionally as alternative medicine

Keywords
plant extracts; antibiotic; Salvadora indica; miswak; Commiphora gileadensis; toxicity; MIC and antitumor

 
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